Carotid Artery Tortuosity Is Associated with Connective Tissue Diseases

Increased vertebral artery tortuosity index is associated with adverse outcomes in children and young adults with connective tissue disorders.

BACKGROUND Arterial tortuosity is described as a common and distinctive feature of Loeys-Dietz syndrome (LDS), yet reports on arterial tortuosity are based on qualitative observations and none have investigated an association between tortuosity and cardiovascular outcomes in LDS or other connective tissue disorders. METHODS AND RESULTS We performed a retrospective analysis of 90 patients ≤50 ...

Immune Components of Liver Damage Associated with Connective Tissue Diseases

Autoimmune connective tissue diseases are associated with liver abnormalities and often have overlapping pathological and clinical manifestations. As a result, they can present great clinical challenges and evoke questions about diagnostic criteria for liver diseases. Moreover, discriminating between liver involvement as a manifestation of connective tissue disease and primary liver disease can...

Autoantibodies Associated With Connective Tissue Diseases: What Meaning for Clinicians?

1 Department of Internal Medicine, Infectious Diseases, and Clinical Immunology, Reims Teaching Hospitals, Robert Debré Hospital, Reims, France, 2 Rheumatology Department, Maison Blanche Hospital, Reims University Hospitals, Reims, France, 3 Laboratory of Dermatology, Faculty of Medicine, EA7319, University of Reims Champagne-Ardenne, Reims, France, 4 Laboratory of Immunology, Reims University ...

Congenital Heart Disease Increased Vertebral Artery Tortuosity Index Is Associated With Adverse Outcomes in Children and Young Adults With Connective Tissue Disorders

Background—Arterial tortuosity is described as a common and distinctive feature of Loeys-Dietz syndrome (LDS), yet reports on arterial tortuosity are based on qualitative observations and none have investigated an association between tortuosity and cardiovascular outcomes in LDS or other connective tissue disorders. Methods and Results—We performed a retrospective analysis of 90 patients 50 yea...

Connective tissue diseases.